S-22 is assistant to the Spectre. Spectre believes Miss Owl is the Owl. When S-22 is ordered to take Belle as her roommate, she expresses her distrust for Belle. Later, she reports Belle sneaking away to try to get a look at Spectre's face.

S-22 preferred suicide to capture by The Owl. It is not explained how she killed herself.

*Crackajack Funnies #36-37
Category:Dell Characters
Category:1941 Debuts
Category:Frank Thomas - Creator
Category:Dead Characters
Category:Non-Powered Characters
Category:Real Name Unknown
Category:Comic Book Characters
Category:Female Villains
Category:Numerically Themed Characters