The dual title character is a doctor who has covered up a secret life full of cruel deeds. Henry Jekyll feels as if he is constantly battling within himself between what is good and what is evil and is pushing away people dear to him. After drinking a potion of his own creation, Jekyll is transformed into the cruel, remorseless, evil Edward Hyde, literally the darkest parts of Dr. Jekyll's nature brought to the forefront.

Dr. Jekyll has many friends including Gabriel John Utterson, Dr. Lanyon, and even a fiance in many adaptations. He has a friendly personality, but as Mr. Hyde, he becomes mysterious, violent, and secretive, and as time goes by, Mr. Hyde grows in power. After taking the potion repetitively, he no longer has to rely upon it to unleash his inner demon.

All published appearances of Dr. Jekyll and Mr. Hyde from before January 1, )-(95)}} are public domain in the US.

Some notable appearances are listed below:

*Strange Case of Dr. Jekyll and Mr. Hyde (1886)

* Dr. Jekyll and Mr. Hyde (1887)
* Dr. Jekyll and Mr. Hyde (1888)
* Dr. Jekyll and Mr. Hyde (1897)
* Dr. Jekyll and Mr. Hyde (1900)

*Dr. Jekyll and Mr. Hyde (1908) - Produced by William N. Selig
*Dr. Jekyll and Mr. Hyde (1908) - Produced by Kalem Films
*A Modern Dr. Jekyll (1909)
*Den skæbnesvangre Opfindelse (1910)
*Dr. Jekyll and Mr. Hyde (1912)
*Dr. Jekyll and Mr. Hyde (1913) - Kinemacolor Company of America
*Dr. Jekyll and Mr. Hyde (1913) - Universal Film Manufacturing Company
*A Strange Case (1914)
*Dr. Jekyll and Mr. Hyde (1920) - Sheldon Lewis
*Dr. Jekyll and Mr. Hyde (1920) - Paramount Pictures

*Have You Got Any Castles (1938)

* Uncle Walt (1964)

*Startling Terror Tales #10
*Kid Eternity #4
*A Star Presentation #3
*This Is Suspense #23
*Nightmare Annual 1972

* ''Climax!'' Season 1 episode 34: ''Dr. Jekyll and Mr. Hyde'' (1955)

* Sambo's Restaurant (1980)

* [https://youtu.be/BeFrWxwE2y4?si=qaq0JkdwdUSMMT8s The Sambo's Restaurant commercial is public domain because it was published in the United States between 1978 and March 1, 1989 without a copyright notice,] [https://publicrecords.copyright.gov/search?page_number=1&query=%22Sambo%27s%20Restaurants%22&field_type=%22keyword%22&records_per_page=10&sort_order=%22asc%22&model= and its copyright was not subsequently registered with the U.S. Copyright Office within 5 years].

*[http://www.comicvine.com/dr-jekyllmr-hyde/29-22215/ ComicVine]
*[http://en.wikipedia.org/wiki/Strange_Case_of_Dr_Jekyll_and_Mr_Hyde Wikipedia]
*[https://fictional-characters-in-media.fandom.com/wiki/Dr._Jekyll_and_Mr._Hyde Fictional Characters in Media Wiki]

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