Isabella I, also known as Isabella the Catholic, was Queen of Castile and León from 1474 until her death in 1504. She was also Queen of Aragon from 1479 until her death as the wife of King Ferdinand II. Reigning together over a dynastically unified Spain, Isabella and Ferdinand are known as the Catholic Monarchs. Her reign marked the end of the Reconquista and also the start of the Spanish Empire, allowing Spain to dominate European politics for the next century.

Isabella's marriage to Ferdinand of Aragon in 1469 created the basis of the de facto unification of Spain. With Ferdinand's help, she won the War of the Castilian Succession, securing her position as Queen of Castile. Isabella reorganized the governmental system, brought the crime rate down, and unburdened the kingdom of the debt which her half-brother King Henry IV had left behind. Her reforms and those she made with her husband had an influence that extended well beyond the borders of their united kingdoms.

Isabella and Ferdinand are known for being the first monarchs to be referred to as the queen and king of Spain, respectively. Their actions included completion of the Reconquista, the Alhambra Decree which ordered the mass expulsion of Jews from Spain, initiating the Spanish Inquisition, financing Christopher Columbus's 1492 voyage to the New World, and establishing the Spanish Empire, making Spain a major power in Europe and the world and ultimately ushering in the Spanish Golden Age.

Together with her husband, Isabella was granted the title of "Catholic Monarch" by Pope Alexander VI, a Spaniard. Her beatification process was opened in 1958, and in 1974 she was granted the title of Servant of God.

All published appearances of Isabella I of Castile before January 1, )-(95)}} are public domain.

Some Notable Appearances are listed below:

* A Picture Story of the United States #1
* Treasure Chest of Fun and Fact #309

* Wikipedia
* [https://comicvine.gamespot.com/isabella-i-of-castile/4005-28496/ Comicvine]
* Historical Figures in Media Wiki
* [https://tvtropes.org/pmwiki/pmwiki.php/UsefulNotes/TheCatholicMonarchs TV Tropes]
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